APPLICATIONS

Extra-vesicles and Exosomes

Exosomes are cell-derived vesicles that are expected to be present in all biological fluids, including blood, urine, and cultured medium of cell cultures. The reported diameter of exosomes in litterature is between 30 and 100 nm. Exosomes are either released from the cell when multivesicular bodies fuse with the plasma membrane or they are released directly from the plasma membrane. Researcher think that exosomes have specialized functions and play a key role in processes such as coagulation, intercellular signaling, and waste management. Consequently, there is a growing interest in the clinical applications of exosomes such as potential prognosis, therapy, and as biomarkers for health and disease. (Source Wikipedia)

Our instruments can measure the following properties of Extra-Vesicles and Exosomes:

  • Hydrodynamic radius
  • Number based concentration
  • Characterisation in complex media
  • Fluorenscence specific tagging