APPLICATIONS

Proteins and antibodies

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific three-dimensional structure that determines its activity. An antibody (Ab), also known as an immunoglobulin (Ig),[1] is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to identify and neutralize pathogens such as bacteria and viruses. (Wikipedia)

Our instruments can measure the following properties of proteins and antibodies:

  • Molecular weight
  • Oligomeric status
  • Hydrodynamic radius
  • Concentration (mass and number)
  • Radius of gyration
  • Conformation
  • Affinity binding
  • Kinetic affinity
  • Stochiometry
  • Active purity
  • Binding enthalpy
  • Stability
  • Viscosity
  • Formulation contaminants