Each of the three models in the Zetasizer Advance Range offers particle size, particle charge (zeta potential) and molecular weight analysis. In addition, each benefits from advances including Adaptive Correlation, M3-PALS zeta potential analysis, constant current zeta mode and Malvern’s deep learning-based data quality advice system. The Ultra has the unique capacity to perform calibration-free particle concentration measurements with ease, even deep into the nano size range. Fit to ISO 13321 and ISO 22412. Typical applications include protein and antibodies, extra-vesicles and exosomes, cells and yeast lysis, small molecules and peptides, liposomes, micelles.