About The Event
Highlighting the system, its applications, and recent progress in fluorescent surface protein tagging of extracellular vesicles (EVs)
This webinar, organized in collaboration with the University of Geneva, will present the capabilities of the NanoSight Pro and its Nanoparticle Tracking Analysis (NTA) technology for advanced nanoparticle characterization.
Expert speakers will cover:
- The system – Technical features of NanoSight Pro and its contribution to precise nanoparticle characterization.
- Applications – Examples of how NTA supports particle size measurement, concentration analysis, quality control, and fluorescence studies.
- Recent advances – Latest innovations in fluorescence labeling of EV surface proteins for biomarker discovery and therapeutic development.
Our Speakers
Aymeric Audfray
Field Application Scientist
MalvernPanalytical
In this presentation, Aymeric Audfray will provide an introduction to the NanoSight Pro system and the ZS Xplorer software. The discussion will focus on the system’s technical capabilities for high-resolution nanoparticle tracking and data analysis. Attendees will learn how the instrument facilitates accurate characterization of size, concentration, and heterogeneity in nanoparticle samples. Several application examples will be presented, including its use in drug delivery research, vaccine development, and the study of nanomaterials. This talk will emphasize how the NanoSight Pro supports both routine measurements and advanced investigations, providing valuable insights for a wide range of scientific fields.
Emie-Kim Ngo Tan
Doctoral Assistant
EPFL
Lipid nanoparticles (LNPs) are the most promissing platform for the delivery of messenger RNA (mRNA), yet their performance strongly depends on efficient and homogeneous loading. Conventional bulk assays report overall encapsulation efficiency but provide limited information on the heterogeneity of individual particles. In this work, we apply nanoparticle tracking analysis (NTA) to quantify the proportion of loaded versus empty LNPs, enabling single-particle resolution of mRNA encapsulation. This approach offers a more precise view of formulation quality and provides critical insights for optimizing LNP design in therapeutic applications.
Sales & Application Specialist
Instrumat AG
Sales & Application Specialist
Instrumat AG
Extracellular vesicles (EVs) are nanoscale particles secreted by most cell types and are powerful biomarkers for many diseases as well as potential therapeutic carriers. Their membranes contain diverse proteins that vary between EV subtypes, allowing for differentiation through targeted fluorescent labelling. Conventional antibody-based labelling, however, often produces weak fluorescence close to the detection threshold.
In this webinar, we will present a novel approach based on MUSE technology. This method combines specific antibody labelling with a two-step amplification process, resulting in a substantially higher ratio of fluorescent markers per antibody than conventional methods. As a result, fluorescence signals are markedly enhanced while background remains low, enabling accurate and reproducible characterisation of EVs.
When
Date & Time: October 7, 2025 – 4 PM (Zürich, UTC+2)
Format: Live online broadcast with Q&A
Join us to gain scientific insights into how NanoSight Pro is contributing to the advancement of particles characterization and EV research.