Malvern Panalytical MicroCal PEAQ-iTC Automated

Fully automated walkway ITC system for increased productivity

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The MicroCal PEAQ-ITC Automated is a configurable, low volume, highly sensitive isothermal titration calorimeter which offers the convenience of unattended operation. It delivers direct, label-free in solution measurement of all binding parameters in a single experiment. Applications include characterizing molecular interactions of small molecules, proteins, antibodies, nucleic acids, lipids and other biomolecules. It can also be used to measure enzyme kinetics. 

Measuring Types

Affinity (KD)
Enthalpy ∆H
Entropy ∆S
Stoichiometry (n)


Isothermal titration microcalorimetry


Sample volume: 370 µL
Cell volume: 200 µL
Injection syringe volume: 40 µL
Injection volume precision: < 1% @ 2 µL
Cell material: hastelloy
Baseline noise: 0.15 ncal/s
Temperature range: 2°C to 80°C
Temperature stability: ± 0.00012°C

Sample Throughput

Up to 42 samples per 24 h (SIM) (automated version)


Intuitive software with streamlined user interface that guides the user to final figures and presentation quality graphs quickly and easily.
Experiment design simulation, batch evaluation of large data sets, automated assessment of data quality
Open multiple experiments in a single session
Supports many automated fitting models


Dimensions 630 x 580 x 770 mm (W, D, H) (calorimeter + wash station)
Weight: 91 kg